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Publications 

  1. Linscott ML, Chung WCJ (2019) TET1 regulates fibroblast growth factor 8 transcription in the mouse embryonic olfactory placode. Epigenetics. Submitted.

  2. Jain S, Chung WCJ, Welshhans KM (2018) Deficits in neural wiring and dysregulated in the Ts65Dn mouse model for Down syndrome. Frontiers in Cellular Neuroscience. Submitted.

  3. Handa RJ, Chung WCJ (2018) Gender and stress. In: Encyclopedia of Stress, Vol. 2. (Fink G Ed). San Diego: Academic Press. In press.

  4. Kim CK, Torcaso A, Asimes AD, Chung WCJ, Pak TR (2018) Structural and functional characteristics of estrogen receptor beta (ERβ) splice variants: implications for the aging brain. Journal of Neuroendocrinology. 

  5. Chung WCJ, Linscott ML, Rodriguez KM, Stewart CE (2016) The role of fibroblast growth factor 8 during neuroendocrine cell development. Frontiers Endocrinology; Experimental Endocrinology. Vol 7: Article 114: 1-7. 

  6. Stewart CE, Corella KM, Samberg BS, Jones P, Linscott ML, Chung WCJ (2016) Fibroblast growth factor 8 murine deficiency delays astrocyte development causing the absence of the corpus callosum. Brain Research. Vol 1646: 287-296. 

  7. Linscott ML, Chung WCJ (2016) Fibroblast growth factor 8 expression in GT1-7 GnRH-secreting neurons is androgen-independent, but can be upregulated by the inhibition of DNA methyltransferases. Frontiers Cell and Developmental Biology. Vol 4: Article 34: 1-9.

  8. Rodriguez KM, Stevenson EL, Stewart CE, Linscott ML, Chung WCJ (2015) Fibroblast growth factor 8 regulates postnatal development of the paraventricular nucleus neurons. Behavioral Brain Functions. Vol 11: 34-42. 

  9. Chung WCJ, Pak TR, Auger AP (2013). Gender differences in neurodevelopment. OA Behavioral Medicine. Vol 1: 3-12. 

  10. Stevenson EL, Corella KM, Chung WCJ (2013). Ontogenesis of gonadotropin-releasing hormone neurons: A developmental model. Frontiers in Experimental Endocrinology. Vol 4: Article 89: 1-8.

  11. Rao YS, Mott NM, Wang Y, Chung WCJ, Pak TR (2013) MicroRNAs in the aging female brain: a putative mechanism for age-specific estrogen effects. Endocrinology. Vol 154: 2795-2806. 

  12. Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung WCJ, et al., (2013) Genetic screening of the FGF8 synexpression group identifies rare sequence variants in FGF17, IL17RD, DUSP6, SPRY4 and FLRT3 in patients with Congenital Hypogonadotropic Hypogonadism. American Journal of Human Genetics. Vol 92: 725-743. 

  13. Chung WCJ, Auger AP (2013). Gender differences neurodevelopment and epigenetics. Pflugers Archiv. Vol 465: 573-584. 

  14. Rochester JR, Chung WCJ, Hayes TB, Tsai PS (2012) Opposite-sex housing reactivates the declining GnRH system in transgenic mice. American Journal of Physiology. Vol 303: 1428-1439. 

  15. Brooks LR, Le DVC, Chung WCJ, Tsai PS (2012) Maternal behavior in transgenic mice with reduced fibroblast growth factor receptor function in GnRH neurons. Behavioral and Brain Functions. Vol 8: 47-55. 

  16. Tata BK, Chung WCJ, and Tsai PS (2012) Fibroblast growth factor signaling deficiencies impact female reproduction and kisspeptin neurons. Biology of Reproduction. Vol 86: Article 119: 1-7. 

  17. Tsai TS, Brooks LR, Rochester JR, Kavanaugh SI, Chung WCJ (2011) Fibroblast growth factor signaling in the developing neuroendocrine hypothalamus. Frontiers of Neuroendocrinology. Vol 32: 95-107. Impact factor: 11.4. Cited: 21.

  18. Pak TR, Chung WCJ (2010) Neuroendocrine Control of Gonadotropins. In: Hormones and Reproduction of Vertebrates, Volume 5, edited by Drs David O. Norris and Kristin H. Lopez. Elsevier. Cited: 1.

  19. Brooks LR, Chung WCJ, Tsai PS (2010). Abnormal hypothalamic oxytocin system in fibroblast growth factor 8 deficient mice. Endocrine. Vol 38: 174-180. 

  20. Mott NN, Chung WCJ, Tsai PS, Pak TR (2010) Fibroblast growth factor 8b regulation of gonadotropin-releasing hormone (GnRH): implications for a developmental switch involving ligand-dependent autoregulation of the receptors FGFR1 and FGFR3. PLoS ONE. Vol 5: e10143:1-8. 

  21. Chung WCJ, Tsai TS (2010) The role of FGF signaling in GnRH neuronal system development. In: Frontiers of Hormone Research (Quinton R Ed.). Basel: S Karger AG. Vol 39: 37-50. 

  22. Chung WCJ, Matthews TA, Tata BK, Tsai PS (2010) Compound deficiencies in multiple FGF signaling components differentially impact the murine GnRH system. J Neuroendocrinology. Vol 22: 944-950. 

  23. Pak TR, Chung WCJ, Hinds LR, Handa RJ (2009) Arginine vasopressin regulation in pre- and post-pubertal male rats by the androgen metabolite 3bdiol. Am J Physiol Endo Metab. Vol 296: E1409-1413. 

  24. Chung WCJ, Moyle SS, Tsai PS (2008) Fibroblast growth factor 8 signaling through FGF receptor 1 is required for gonadotropin-releasing hormone neuronal development in mice. Endocrinology. Vol 149: 4997-5003. 

  25. Falardeau J, Chung WCJ, Beekeen A, Plummer L, Sidis Y, Raivio T, Dwyer A, Na S, Hall J, Huot C, Alois N, Quinton R, Cole LW, Hughes V, Mohammadi M, Tsai PS, Pitteloud N (2008). Decreased FGF8 signaling causes GnRH deficiency in human and mice. Journal Clinical Investigations. Vol 118: 2822-2831. 

  26. Handa RJ, Chung WCJ (2007) Gender and stress. In: Encyclopedia of Stress, Vol. 2. (Fink G Ed). San Diego: Academic Press: 115-121. Cited: 4.

  27. Chung WCJ, Pak TR, Suzuki S, Pouliot WA, Andersen ME, Handa RJ (2007). Detection and localization of an estrogen receptor beta splice variant protein (ERb2) in the adult female rat forebrain and midbrain regions. Journal Comparative Neurology. Vol 20: 249-267. 

  28. Pak TR, Chung WCJ, Hinds LR, Handa RJ (2007) Estrogen receptor-beta mediates DHT-induced stimulation of the arginine vasopressin promoter in neuronal cells. Endocrinology. Vol 148: 3371-3382. 

  29. Handa RJ, Chung WCJ, Thomas RS, Andersen ME (2006) Estrogen receptor signaling in sexual differentiation of the brain: Can we teach an old dogma new tricks? Neurotoxicology. Vol 27: 889-890 Sp. Iss.

  30. Chung WCJ, Pak TR, Weiser M, Hinds LR, Andersen ME, Handa RJ (2006) Progestin receptor expression in the developing rat brain depends upon activation of estrogen receptor a and not estrogen receptor b. Brain Research. Vol 1082: 50-60.

  31. Pak TR, Chung WCJ, Roberts JL, Handa RJ (2006) Ligand-independent effects of estrogen receptor beta on mouse gonadotropin releasing hormone (GnRH) promoter activity. Endocrinology. Vol 147: 1924-1931. 

  32. Lund TD, Rovis T, Chung WCJ, Handa RJ (2005) Novel actions of estrogen receptor beta on anxiety-related behaviors. Endocrinology. Vol 146: 797-807. 

  33. Pak TR, Chung WCJ, Lund TD, Hinds LR, Clay CM, Handa RJ (2005) The androgen metabolite, 5a-androstane-3b, 17b-diol (3bAdiol), is a potent modulator of estrogen receptor b-1-mediated gene transcription in neuronal cells. Endocrinology. Vol 146: 147‑155. 

  34. Swaab DF, Chung WCJ, Kruijver FPM, Hofman MA, Hestiano A (2003) Sex differences in the hypothalamus in the different stages of human life. Neurobiology of Aging. Vol 24 Supplement 1: S1-S16. 

  35. Quadros PS, Lopez V, De Vries GJ, Chung WCJ, Wagner CK (2002) Progesterone receptors and the sexual differentiation of the medial preoptic nucleus. Journal of Neurobiology. Vol 51: 24-32. 

  36. Chung WCJ, De Vries GJ, Swaab DF (2002) Sexual differentiation in the bed nucleus of the stria terminalis of the human extends into adulthood. Journal of Neuroscience. Vol 22: 1027-1033. 

  37. Swaab DF, Chung WCJ, Kruijver FPM, Hofman MA, Ishunina TA (2002) Sexual differentiation of the human hypothalamus. Advanced Experimental Medical Biology. Vol 511: 75-105.

  38. Swaab DF, Chung WCJ, Kruijver FPM, Hofman MA, Ishunina TA (2001) Structural sex differences in the human hypothalamus. Hormones and Behavior. Vol 40: 93-98.  

  39. Chung WCJ, Swaab DF, De Vries GJ (2000) Apoptosis during postnatal sexual differentiation of the bed nucleus of the stria terminalis in the rat brain. Journal of Neurobiology. Vol 43: 234-243. 

  40. Lucassen PJ, Chung WCJ, Kamphorst W, Swaab DF (1997) DNA damage distribution in the human brain as shown by in situ end labeling; Area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology. Journal of Neuropathology Experimental Neurology. Vol 56: 887-900.

  41. Lucassen PJ, Chung WCJ, Vermeulen JP, Lookeren van Campagne M, Swaab DF (1995) Microwave enhanced in situ end-labeling of fragmented DNA; parametric studies in relation to post mortem delay and fixation of the rat and human brain. Journal of Histochemistry and Cytochemistry. Vol 43: 1163-1171. 

  42. Lucassen PJ, Williams A, Chung WCJ, Fraser H (1995). Detection of apoptosis in murine scrapie. Neuroscience Letters. Vol 198: 185-188. 

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